尊龙时凯

    Partnering

    Broaden the pipeline and enhance innovation efficiency through license-in/outs

    License out

    2018

    JAK1 inhibitor SHR0302 out-licensed to Arcutis (USA)

    BTK inhibitor SHR1459 out-licensed to TG Therapeutics (USA)

    2020

    Camrelizumab out-licensed to Crystal Genomics (South Korea)

    Pyrotinib out-licensed to HLB-LS (South Korea)

    SHR-1701 out-licensed to DONG-A ST CO., LTD. (South Korea)

    2023

    EZH2 inhibitor SHR2554 out-licensed to Treeline Biosciences (USA)

    TSLP McAb (SHR-1905) out-licensed to Aiolos Bio (USA)

    HER1/HER2/HER4 targeted drug (Pyrotinib maleate tablets) out-licensed to Dr.Reddy's (India)

    Combination therapy of PD-1 inhibitor Camrelizumab for liver cancer out-licensed to Elevar Therapeutics (USA)

    PARP1 inhibitor HRS-1167, Claudin-18.2 ADC SHR-A1904 out-licensed to Merck KGaA (Germany)

    2024

    Product portfolio of GLP-1 innovative drugs out-licensed to Kailera (USA)

    DLL3 ADC innovative drug (SHR-4849) out-licensed to IDEAYA Biosciences (USA)

    2025

    Lp(a) inhibitor (HRS-5346) out-licensed to MSD

    Cooperation with Merck KGaA (Germany) to promote the commercialization of oral GnRH antagonists

    Cooperation with GSK to develop up to 12 innovative drugs covering Respiratory, Immunology & Inflammation(RI&I) and Oncology, including an worldwide

    license (excluding mainland China, Hong Kong SAR, Macau SAR and Taiwan region) for PDE3/4 inhibitor HRS-9821

    Myosin inhibitor (HRS-1893) out-licensed to Braveheart Bio

    License in

    2019

    Antifungal product VT-1161 introduced from Mycovia (USA) has been approved for sale with the name of Oteseconazole

    CyclASol® and NOV03, drugs for xerophthalmia introduced from Novaliq (Germany)

    2021

    A strategic cooperation reached with YL-PHARMA on a breakthrough therapy (PI3kδ inhibitor), which has been approved for sale as Linperlisib.

    A strategic cooperation reached with Cstone Pharmaceuticals on anti-CTLA-4 McAb (CS1002)

    In License

    Out License

    Strategic Collaboration

    Co-Development